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DNA Damage: Oxidative stress can inflict DNA damage, hinder DNA repair mechanisms, and promote cell proliferation, facilitating lung cancer development (Stefanou et al., 2022)

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12, 16, 18 A high degree of synergistic enhancement of L-PAM cytotoxicity in the presence of BSO was observed in multidrug-resistant neuroblastoma cell lines, including those that were established at relapse after myeloablative therapy with L-PAM and lines highly resistant to L-PAM due to loss of p53 function, especially at concentrations of L-PAM that were myeloablative

If the dose, purity, route of administration or patient selection is wrong, the risk profile changes

This ingestion of carbohydrates is followed by the proliferation of lactate-producing microorganisms, such as Streptococcus bovis , which metabolizes carbohydrates to L (+) and D (-) lactate

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